Different Patterns of Intraerythrocytic Inclusion Body Distribution in the Two Types of Haemoglobin H Disease: An Ultrastructural Study
ชื่อเรื่อง
Different Patterns of Intraerythrocytic Inclusion Body Distribution in the Two Types of Haemoglobin H Disease: An Ultrastructural Study
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ผู้สร้าง/เจ้าของผลงาน
Bunyaratvej, Ahnond
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Sahaphong, Somphong
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Bhamarapravati, Natth
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Wasi, Prawase
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หัวเรื่อง
Hematology
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Oncology
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บทคัดย่อ
Electron microscopic examination of intraerythrocytic inclusion bodies induced by methylene blue was carried out in 7 non-splenectomized patients with haemoglobin (Hb) H disease. In classical Hb H disease with the genotype of α-thalassaemia 1/α-thalassaemia 2 the inclusion bodies were mostly membrane-associated. In contrast, in Hb H disease of α-thalassaemia 1/Hb Constant Spring genotype the majority of inclusion bodies were in a floating stage. Possible mechanisms for the unexpected difference are discussed.
ผู้ร่วมงาน
Department of Pathology, Ramathibodi Hospital, Mahidol University,
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Department of Pathobiology, Faculty of Science, Mahidol University
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Department of Pathology, Ramathibodi Hospital, Mahidol University,
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Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
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ปีที่ผลิตเอกสาร
วันที่บันทึกข้อมูล
2023-05-02
ประเภท
Article
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รูปแบบ
ขนาดหรือจำนวนของเอกสาร
5 pages
ต้นฉบับ/แหล่งที่มาของเอกสาร
Acta Haematologica, Vol., 69, No. 5, Page 314–318
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รหัส หรือตัวบ่งชี้เอกสาร
ขอบเขต
เจ้าของลิขสิทธิ์
S. Karger AG, Basel
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