Alpha- and beta-thalassemia in Thailand

ชื่อเรื่อง

Alpha- and beta-thalassemia in Thailand See all items with this value

ผู้สร้าง/เจ้าของผลงาน

Wasi, Prawase
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Na-Nakorn, Supa
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Pootrakul, Sa-nga
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Sookanek, Munsit
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Disthasongchan, Pensri
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Pornpatkul, Malida
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Panich, Vicharn See all items with this value

หัวเรื่อง

History and Philosophy of Science
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General Biochemistry, Genetics and Molecular Biology
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General Neuroscience See all items with this value

คำอธิบายรายละเอียดของเอกสาร

This study was supported by United States Public Health Service Grant AM 09805 from the National Institute of Arthritis and Metabolic Diseases.

บทคัดย่อ

In Thailand, both a- and ß-thalassemia are widespread and there is more than one subtype in each variety. Hemoglobin (Hb) E which is is a2, p;6G'u+L (Hunt & Ingram, 1959) is remarkably frequent (Na-Nakorn et al., 1956; Sundharagiati et al. 1958, 1959a, 1959b; Flatz et al., 1965; Wasi et al., 1967a), reaching 50 percent in certain areas. These abnormal genes in different combinations result in a spectrum of syndromes ranging from asymptomatic heterozygotes to lethal Hb Bart's hydrops fetalis. Attempts have been made to characterize the various genotypes by clinical, hematologic, biochemical, genetic and cord blood studies. This paper summarizes the manifestations of these syndromes, with particular emphasis on the
diseased forms

ผู้ร่วมงาน

Division of Hematology. Department of Medicine Siriraj Hospital Medical School. Bangkok, Thailand See all items with this value

ปีที่ผลิตเอกสาร

1969 See all items with this value

วันที่บันทึกข้อมูล

2023-04-28

ประเภท

Article See all items with this value

รูปแบบ

pdf See all items with this value

ขนาดหรือจำนวนของเอกสาร

23 pages

ต้นฉบับ/แหล่งที่มาของเอกสาร

Annals of the New York Academy of Sciences, Vol. 165, Page 60-82

ภาษา

en See all items with this value

รหัส หรือตัวบ่งชี้เอกสาร

https://doi.org/10.1111/j.1749-6632.1969.tb27777.x See all items with this value

ขอบเขต

Health See all items with this value

เจ้าของลิขสิทธิ์

John Wiley & Sons, Inc. See all items with this value

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