The Mechanism of the Development of Anemia in Untreated Chronic Lymphatic Leukemia

ชื่อเรื่อง

The Mechanism of the Development of Anemia in Untreated Chronic Lymphatic Leukemia
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ผู้สร้าง/เจ้าของผลงาน

Wasi, Prawase
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Block, Matthew
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หัวเรื่อง

Anemia etiology
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Humans
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Leukemia See all items with this value

Lymphocytic See all items with this value

Chronic See all items with this value

B-Cell
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Lymphoid complications See all items with this value

คำอธิบายรายละเอียดของเอกสาร

This article was supported by H. M. King Bhumipol Adulyadet of Thailand

บทคัดย่อ

ANEMIA is part of the natural history of chronic lymphatic leukemia. The A etiology of the anemia has been attributed to a decreased rate of red cell production and to an increased rate of red cell destruction. Prior studies have been based on estimations of (1) the amount of erythroblastic tissue found in smears of aspirated bone marrow and in sections of the marrow at autopsy; (2) the red cell survival by Ashby or radiochromium technics; and (3) the rate of red cell formation by radioiron technics and reticulocyte counts. Furthermore, investigators of this problem generally have not taken into account the effect of therapy on the development of anemia. The purpose of this investigation was to study the interrelationships of the peripheral blood findings, the histopathology of the bone marrow, and the red blood cell survival in order to elucidate the mechanism by which anemia develops in patients with untreated chronic lymphatic leukemia.

ผู้ร่วมงาน

Department of Medicine, University of Colorado Medical Center, Denver, Colo. See all items with this value

ปีที่ผลิตเอกสาร

1961
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วันที่บันทึกข้อมูล

2023-04-27

ประเภท

Article
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รูปแบบ

pdf See all items with this value

ขนาดหรือจำนวนของเอกสาร

13 Pages

ต้นฉบับ/แหล่งที่มาของเอกสาร

Blood Vol. 17, No. 5, Page 597–609

ภาษา

en See all items with this value

รหัส หรือตัวบ่งชี้เอกสาร

https://doi.org/10.1182/blood.V17.5.597.597 See all items with this value

ขอบเขต

Health See all items with this value

เจ้าของลิขสิทธิ์

American Society of Hematology See all items with this value

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